Ozempic, GLP-1 and cellulite

After 25 years of focusing on cellulite reduction one thing is very clear: cellulite may be a fat accumulation problem but it is also a connective tissue and circulation problem too, so mere fat reduction is not enough to solve this puzzle, especially when fat reduction, with GLP-1 drugs or otherwise, typically occurs on less stubborn areas, not those afflicted with cellulite. Read more…
— Georgios Tzenichristos, LipoTherapeia | London

Will Ozempic and other GLP-1 drugs eliminate cellulite?

Ozempic, Wegovy, Mounjaro and overweight/obesity

The rise of current GLP-1 receptor agonist drugs, such as ozempic/wegovy and mounjaro, and the development of new ones with less side effects and possible oral administration (as opposed to current injection), is poised to reduce the incidence of overweight and obesity in the general population.

However, can Ozempic/Wegovy, Mounjaro et al eliminate the cellulite appearance?

Existing severe cellulite after GLP-1 drug administration

GLP-1 drugs can indeed reduce or eliminate overweight or obesity. However, cellulite in overweight and obese people is always already very established, causing permanent changes in the connective tissue, so it cannot be eliminated just with a GLP-1 agonist receptor medication.

Sure, adipocytes will empty to a large extent in the areas affected by cellulite but they will not empty completely (that would require someone to become extremely thin). Furthermore, the hypodermal fibrosis found in cellulite will stay. Plus the overall skin laxity left after the removal of fat will also stay, further accentuating the appearance of cellulite.

The best possible treatment for such residual cellulite and skin laxity is deep-acting, high-power radiofrequency combined with deep-acting, high-power ultrasound cavitation.

> At LipoTherapeia® | London we research, study and practice the science of cellulite and skin tightening daily, in order to offer you the best possible information, advice and treatment. Learn more at lipotherapeia.com.

Existing mild cellulite after GLP-1 drug administration

At the moment such medication is not given to non-overweight people, i.e. the people who may only have mild or average cellulite.

In the case of mild cellulite, i.e. cellulite which did not have a chance to create much fibrosis in the hypodermis, where adipocytes are not excessively sized and where dermis did not end up becoming too loose, such medication may lead to considerable reduction of cellulite.

(Existing “average” cellulite, i.e. neither mild nor severe cellulite, will be reduced to a large extent but not considerably.)

Whatever remains of such mild/average cellulite, and the skin laxity that accompanies it, can be completely eliminated with the combination of deep, strong RF/cavitation, as mentioned above.

But that remains a future scenario, if and when such medication is prescribed to much slimmer people than today.

Cellulite prevention with GLP-1 medication?

If in the future GLP-1 receptor agonist medication becomes almost adverse reaction-free (no drug can ever be 100% adverse reaction-free) and is taken by most members of the public, in that case, yes, cellulite may never develop in most of those people.

I used the words “may” and “most” in the above paragraph because cellulite can also be caused by inactivity, water retention, inflammation, different drugs etc, so even if we generally inhibit hypodermal fat accumulation with medication (again, there is no guarantee of 100% hypodermal fat accumulation), some people may still develop cellulite.

But at the moment we cannot be sure if such super-safe medication will exist and this option remains science fiction.

LipoTherapeia® Plus: Have a skin tightening/cellulite treatment with London’s cellulite experts

At LipoTherapeia we have specialised 100% in skin tightening and cellulite reduction for more than two decades and 20,000+ sessions.

This is all we study and practise every day and have researched and tried hands-on all the important skin tightening equipment and their manufacturers.

As strong, deep acting radiofrequency and deep-acting, high-power ultrasound cavitation are the technologies of choice for skin tightening and cellulite reduction, we have invested in the best RF/ultrasound technologies in the world.

(Of course, we keep looking for new technologies every day and if/when a better technology materialises we will be the first to provide it. However, we will never follow the latest ineffective gimmick, just because it’s good marketing to offer the latest hyped up - yet ineffective and/or unsafe treatment.)

Furthermore, over the last two decades we have developed advanced RF and cavitation treatment protocols in order to make the most of our technologies, for maximum results, naturally and safely.

And for even better, faster results, we now combine our RF/ultrasound treatments with high-power red/infrared light LED treatment.

Our radiofrequency/ultrasound/LED treatments are comfortable, pain-free, downtime-free, injection-free, 99.5%+ safe and always non-invasive.

(No unsafe and ineffective RF microneedling or HIFU and no safe but ineffective acoustic wave therapy, superficial RF (bipolar/tripolar/multipolar etc), low power RF/cavitation, electrical muscle stimulation, lymphatic massage, cupping, dry brushing and no ridiculous bum bum creams.)

Our focus is on honest, realistic, science-based treatment, combined with caring, professional service, with a smile.

We will be pleased to see you, assess your cellulite, skin laxity or fibrosis, listen to your story, discuss your case and offer you the best possible treatment.

Check prices and book an expert cellulite / skin tightening treatment at our London clinic.

Look Inside Your Skin™ with a Cellulite Ultrasonography™ scan, exclusive to LipoTherapeia in London, and assess your cellulite, skin laxity, post-liposuction fibrosis and more

We are proud to be the first and only cellulite clinic in the world to offer Cellulite Ultrasonography™ to our clients, for accurate assessment, better treatment and enhanced results. Since 2022 we have assessed and provided valuable insights to hundreds of clients to better understand their specific case, see how their skin looks from inside and make informed decisions.

You can now book your Cellulite Ultrasonography™ session and assess your:

  • Cellulite

  • Skin laxity

  • Lipedema

  • Subcutaneous fat levels

You can also assess the presence and severity of fibrosis and adhesions after:

  • Liposuction in all its forms, including vaser, smart lipo, bodytite, abdominoplasty/tummy tuck, thigh lift, arm lift, lipedema surgery etc

  • Cellulite surgery, such as cellulaze, cellutite, cellfina, subcision etc

  • Face-lift surgery

  • Non-surgical procedures, such as RF microneedling, extreme intensity HIFU, extreme intensity RF, extreme intensity ultrasound etc

Everything will be shown and explained to you clearly and you can see and understand how the different structures inside your skin affect your appearance.

If there is scar tissue / fibrosis, those will be clearly seen and you can differentiate between fibrosis, water retention or unremoved fat after all types of cosmetic surgery or harsh non-surgical procedures such as RF microneedling, extreme intensity HIFU etc.

(DISCLAIMER: Please note that this service is for your informational purposes only and does not constitute medical diagnosis or advice.)

The 45’ appointment includes full assessment and consultation and optional treatment plan for cellulite reduction and/or skin tightening.

If you do wish to have treatment with us, the ultrasound scan, assessment and consultation will be used to optimise your course of treatments and maximise your results.

Check prices and book an expert skin / superficial connective tissue ultrasound scan at our London clinic.

The Cellulite School™: Get advanced training in cellulite reduction and skin tightening

Why train with The Cellulite School™?

We all know that training in cellulite reduction and skin tightening is as basic as it gets. It is typically a 4-6 hour training, involving only basic instruction from the manufacturer on how operators can use the machine; lots of myths, erroneous information and misconceptions; and some basic health and safety on how to use the machine.

There is no proper, real training in the science or cellulite, skin tightening, radiofrequency, ultrasound and all related technologies is non-existent - worldwide.

Do you want to deeply understand radiofrequency, ultrasound cavitation, LED phototherapy, cellulite and skin tightening?

Get proper training based on 24-year theory and practical application of cellulite reduction and valuable insights from 23,000+ sessions and 4,100+ clients.

Now you can get instant access to our expertise and save yourself literally thousands of pounds, dollars or euros of expensive mistakes and thousands of hours of study, research and practical application by attending one of our half-day, 1-day, 2-day or 3-day professional consultancy / training courses.

Understand deeply - and get properly trained in - the science of radiofrequency, ultrasound cavitation, LED phototherapy, cellulite and skin tightening and confidently offer your clients the safest, strongest and most effective treatment possible.

Service available via Zoom or at our central London practice.

Learn more or check prices and book training at our London clinic or via Zoom.