Germinated brown rice extract suppresses weight gain and reduces cholesterol and triglycerides
Recent research suggests that germinated brown rice can help fight weight gain by reducing fat accumulation and can also reduce the side-effects of weight gain by reducing cholesterol levels.
Specifically, researchers in Korea have found that germinated brown rice significantly decreased body weight gain and lipid accumulation in the liver and adipose tissue. In addition, triglycerides and total cholesterol levels (both detrimental to health) were significantly decreased with the germinated brown rice extract, while the levels of "good cholesterol" (high-density lipoprotein, HDL) increased.
The researchers found that the these results where all due to the significant reduction in the expression of genes responsible for fat accumulation, such as PPAR-gamma.
Another traditionally consumed food helps fight the "flab"...
The researchers concluded that "these results suggest that germinated brown rice is a potential agent against obesity". Practically speaking, germinated brown rice can help reduce weight gain, either in the form of raw food or in the form of food supplement.
Extracts of germinated brown rice are also be available, offering the concentrated benefit of this anti-obesity food. However, you can best take advantage of this research by incorporating healthful brown rice sprouts into your salads. Sprouted brown rice is already found in health food stores and brown rice sprouts can also be easily made at home.
- Paper: Anti-Obesity Effects of Germinated Brown Rice Extract through Down-Regulation of Lipogenic Genes in High Fat Diet-Induced Obese Mice
- Abstract: Lipid accumulation using Oil Red O dye was measured in 3T3-L1 murine adipocytes to examine the anti-obesity effect of four types of germinated rice, including germinated brown rice (GBR), germinated waxy brown rice (GWBR), germinated black rice (GB-R), and germinated waxy black rice (GWB-R). GBR methanol extract exhibited the highest suppression of lipid accumulation in the 3T3-L1 cell line and also the anti-obesity effect of GBR on high fat induced-obese mice. The mice were divided into three groups and were administered: ND, a normal diet; HFD control, a high fat diet; and GBR, a high fat diet plus 0.15% GBR methanol extract for 7 weeks. GBR administration significantly decreased body weight gain and lipid accumulation in the liver and epididymal adipose tissue as compared to the HFD control group. In addition, serum triglycerides (TGs) and total cholesterol (TC) levels were significantly decreased by following GBR administration compared with those in the HFD control group, whereas the high-density lipoprotein (HDL) cholesterol level increased. Furthermore, the mRNA levels of adipogenic transcriptional factors, such as CCAAT enhancer binding protein (C/EBP)-α, sterol regulatory element-binding protein (SREBP)-1c, and peroxisome proliferator activated receptors (PPAR)-γ, and related genes (aP2, FAS), decreased significantly. Taken together, GBR administration suppressed body weight gain and lipid accumulation in the liver and epididymal adipocytes, and improved serum lipid profiles, in part, by controlling adipogenesis through a reduction in transcriptional factors. These results suggest that GBR is a potential agent against obesity.