- In this university study, performed by two Italian universities over two years, it was found that a herbal compound, in combination with compression garments containing multiple active ingredients, significantly improved inflammation, healing time and pain in phlebitis, in relation to compression garments alone.
- The authors suggest that ivy extract in the cream contributed to pain reduction; horse chestnut, butcher's broom and grape seed extract reduced inflammation; and allantoin, gotu kola and hyaluronic acid aided to sore healing.
- In patients who applied both the cream and the compression garment pain stopped in 72 hours, inflammation disappeared in one week, tissue swelling stopped in one week and healing was complete in 4 weeks!
- This study demonstrates the absorption and efficacy of multi-ingredient creams in circulatory and inflammatory disorders, and the effectiveness of the natural actives gotu kola, horse chestnut, allantoin and hyaluronic acid, among others. These same actives are used in anti-cellulite and leg wellness creams for the same reasons: circulation improvement, tissue repair and inflammation reduction, all important aspects of cellulite reduction.
- Source: Multicentric study on a topical compound with lymph-draining action in the treatment of the phlebostatic ulcer of the inferior limbs].
- Abstract: Phlebostatic sore of the lower limbs is a typical chronic venous insufficiency complication and is still a widely controversial issue in its treatment. The common therapies, in fact, are not yet standardized and they not show complete efficacy. Since 2005 to 2007 a multicentric clinical trial was conducted at the Plastic and Reconstructive Surgery of "Sapienza" University of Rome and at the Plastic and Reconstructive Surgery Department, University of Perugia, in order to evaluate the efficacy of the Idrastin lymph-draining cream in patients with phlebostatic sores of the lower limbs. This study enrolled on 80 patients, split into 2 homogeneous groups of 40 patients: group A was treated by only elastocompressive therapy, group B by elastocompressive therapy and Idrastin. Multicentric analysis has considered the following parameters: local pain, perilesional flogosis , granulation tissue, perilesional tissue tropism healing time. In the group B results highlighted: reduction of the local pain, stopped in 72 hours; flogosis decrease disappeared in one week; tissue granulation growth in one week; lesion healing in 4 weeks. These results pointed out statistically significance of the variables considered. In our opinion Idrastin compounds such as phytoessence of hops and Hedera helix, had contributed to analgesia; Aesculus hippocastanum, and Vitis vinifera and Ruscus aculeatus phytoessence showed anti-flogistic action; allantoin and Centella asiatica and hyaluronic acid aided to sore healing. Idrastin gives an effective support to the treatment of the phlebostatic sores warrants a faster and more effective healing process, than to the wounds treated by only the elastocompressive therapy.
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