Polyphenols: the most important anti-ageing cream active ingredients

  • Plant polyphenols are the most impressive natural anti-ageing cream active ingredients.
  • Most have strong antioxidant action, some act as anti-inflammatory, many prevent the loss of collagen and elastin that occurs from metalloproteinases (thereby preserving skin firmness), several boost collagen production, while other protect against skin damage caused by the sun
  • Extracts of green tea, pine bark, grape seed, gotu kola, cocoa, citrus fruits, berries, green coffee are examples of some important polyphenols containing herbs that are used in anti-ageing / skin firming creams.
  • Source: Polyphenols as active ingredients for cosmetic products
  • Abstract: Polyphenols are secondary plant metabolites with antioxidant, anti-inflammatory and antimicrobial activity. They are ubiquitously distributed in the plant kingdom; high amounts contain e.g. green tea and grape seeds. Polyphenolic extracts are attractive ingredients for cosmetics and pharmacy due to their beneficial biological properties. This review summarizes the effects of polyphenols in the context of anti-aging activity. We have explored in vitro studies, which investigate antioxidant activity, inhibition of dermal proteases and photoprotective activity, mostly studied using dermal fibroblasts or epidermal keratinocytes cell lines. Possible negative effects of polyphenols were also discussed. Further, some physicochemical aspects, namely the possible interactions with emulsifiers and the influence of the cosmetic formulation on the skin delivery, were reported. Finally, few clinical studies, which cover the anti-aging action of polyphenols on the skin after topical application, were reviewed.