- The combination of Ruscus aculeatus (butcher's broom), hesperidin methyl chalcone (HMC) and ascorbic acid has been tested before on patients with lower limb chronic venous insufficiency and was found effective in reducing water retention and improving vein tone.
- In this study patients with chronic venous disorders (CVD) were assessed after 12 weeks of taking a nutritional supplement comprising of the three actives mentioned above.
- At the conclusion of the study it was found that "all clinical symptoms significantly improved with treatment, especially for patients with higher body mass index and heavier pathology. Ankle circumference, which reveals the extension of water retention decreased over time, gradually decreased and both the physical and psychological dimensions of quality of life significantly increased over time and improved in all types of patients.
- The researchers concluded that" "A 12-week treatment with ruscus aculeatus, HMC and ascorbic acid showed a significant decrease in clinical symptoms and a significant improvement in the quality of life of patients with chronic venous disorder".
- The results are unsurprising, given the well-studied circulation-enhancing and blood vessel-protecting effects these separate actives have on their own.
- Given that poor circulation is an important aspect of cellulite, this combination is also ideal for the treatment of cellulite, both when taken orally (food supplement) or applied locally (cellulite cream). Other active ingredients, in addition to the above three, would offer enhanced synergy and maximum results.
- Source: Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl chalcone and ascorbic acid (quality study).
- Abstract: AIM: The present study assessed the effect of Ruscus aculeatus, hesperidin methyl-chalcone and ascorbic acid (HMC-AA), in the treatment of chronic venous disorders (CVD) in Latin American patients. METHODS: This study is an observational, single arm, multicentric and prospective trial. Patients suffering from CVD and belonging to C0s-C3 Clinical Etiological Anatomical and Physiopathological (CEAP) classes were included. Patient profiles, risk factors, clinical symptomatology and quality of life (QoL) assessed by SF-12 and CIVIQ questionnaires were evaluated at inclusion and after 12-week treatment. RESULTS: The main factors influencing the previous management of patients were age, gender, body mass index (BMI), familial history, physical activity, exposure to heat, heavy loads lifting, profession and clinical characteristics. All clinical symptoms significantly improved with treatment and, as BMI and CEAP classes increased. Ankle circumferences decreased over time, correlating with BMI and CEAP classes. The physical and psychological dimensions of the SF-12 score significantly increased over time and improved within each CEAP class. The CIVIQ score significantly improved over time, correlating with age and CEAP classes. CONCLUSION: A 12-week treatment with Ruscus aculeatus HMC-AA showed a significant decrease in the clinical symptoms and a significant improvement in the QoL of patients with CVD.
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