- In this study on 87 patients over two months it was found that concentrated gotu kola / centella asiatica extract improves circulation and tissue oxygen levels and reduces venous hypertension, venous inflammation and carbon dioxide levels, with higher doses poroducing better results.
- Gotu kola is very well established as a circulation-boosting, vein health-protecting active, and due to these properties it is used in both food supplements and leg wellness / anti-cellulite creams.
- Source: The microcirculatory activity of Centella asiatica in venous insufficiency. A double-blind study
- Abstract: In 87 patients with chronic venous hypertensive microangiopathy the efficacy of oral FTTCA (Centella asiatica) administered for 60 days was tested. The microcirculatory effects of two dosages (30 mg bid and 60 mg bid) versus placebo was assessed in a double blind study. The compound was well tolerated and no unwanted effects were observed. Microcirculatory parameters--peri-malleolar skin flux at rest (RF) and transcutaneous PO2 and PCO2--improved as did the abnormally increased RF, PCO2 decreased and PO2 increased in comparison with values measured at inclusion. These results confirm the efficacy of FTTCA in venous hypertensive microangiopathy. Furthermore the effects of FTTCA appear to be dose-related.
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