Exercise and superficial fat tissue / cellulite

  • It is now well established that exercise increases the protein UCP1 in fat cells, especially those fat cells under the skin (subcutaneous adipose tissue) and inside the skin (cellulite). This consequently turns fat-storing white fat cells into fat-burning "beige" fat cells. In this way, exercise helps you lose fat both by burning fat in muscles and by burning fat in fat cells themselves.
  • Now a new paper published on the journal Diabetes reports that exercise training results in changes in thousands of genes that affect subcutaneous adipose tissue and in adipokines on both subcutaneous adipose tissue and visceral adipose tissue (deep stomach fat), with beneficial effects against diabetes, whole body inflammation and heart disease (adipokines are hormone-like substances produced by fat tissue and have multiple implications in whole body health).
  • Even more impressive is the fact that fat cells taken from trained mice and transplanted into sedentary mice continue to behave as if they belong to a trained animal and cause beneficial body-wide changes in metabolism and overall health!
  • In summary, the beneficial changes in whole-body metabolic health that exercise training causes, are to a large extent due to the profound effects of exercise on fat tissue itself, especially superficial fat tissue.
  • Source: Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations, http://www.ncbi.nlm.nih.gov/pubmed/26050668/