Effectiveness evaluation of an anti-cellulite cream containing retinol, caffeine and ruscogenin

  • Retinol, caffeine and ruscogenin (butcher's broom extract) are well-known natural anti-cellulite chemicals, which are used, in lower or higher concentrations, in many anti-cellulite creams.
  • In this study, the efficacy of a cream containing the combination of all three actives was tried on a group of 46 women for 84 days.
  • Skin texture, dermal and hypodermal structures, mechanical characteristics and superficial blood circulation were assessed using several non-invasive methods.
  • At the end of the study the researchers concluded that both the orange peel appearance as well as circulation were significantly improved, in relation to placebo: "The association of the three tested active ingredients was significantly active on the 'orange peel' appearance of the skin, which is the most apparent manifestation of cellulite (53.1% at T84 versus 14.1% for the placebo)"
  • "This combination of different evaluation methods resulted in the demonstration of significant activity of the anti-cellulite product versus baseline and showed its superiority versus the placebo in skin macrorelief (decrease of the "orange peel" effect) and an increase in cutaneous microcirculation"
  • Clearly, cellulite creams do get absorbed (contrary to the urban myth that creams do not get absorbed) and they do work, especially if multiple natural actives are combined - especially in high concentrations.
  • Source: A double-blind evaluation of the activity of an anti-cellulite product containing retinol, caffeine, and ruscogenin by a combination of several non-invasive methods.
  • Abstract:  A double-blind, randomized, placebo-controlled study was conducted with 46 healthy female volunteers in order to test an anti-cellulite product containing retinol, caffeine and ruscogenine. An evaluation of different parameters related to cellulite appearance, i.e. the skin macrorelief, the dermal and hypodermal structures, the skin mechanical characteristics, and the cutaneous flowmetry was assessed using several non-invasive methods. This combination of different evaluation methods resulted in the demonstration of significant activity of the anti-cellulite product versus baseline and showed its superiority versus the placebo in skin macrorelief (decrease of the "orange peel" effect) and an increase in cutaneous microcirculation. By using a combination of methods, it was possible to detail the activity of an anti-cellulite product and to show superiority of the product in comparison with the placebo.

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