- The botanical extract of ruscus aculeatus (butcher's broom), comprising the steroidal sapogenins ruscogenin and neoruscogenin, is used against haemorrhoids, chronic venous insufficiency, improvement of venous tone and stimulation of lymphatic drainage.
- Among other studies, a double-blind study on healthy volunteers showed a significant decrease in venous capacity and tissue volume.
- Due to it's effect on circulation improvement and lymph drainage, ruscogenins from butcher's broom are important actives in circulation-assisting and anti-cellulite creams and nutritional supplements, - ideally in combination with multiple similar natural actives, such as escin and rutin, for enhanced synergy.
- Source: Der stechende Mäusedorn - Ruscus aculeatus L.
- Abstract: Ruscus aculeatus is a medicinal plant of the Mediterranean region. This review covers its botany, composition, pharmacology, pharmacokinetics, toxicity and clinical use. Extracts of the underground parts are mainly used to treat chronic venous insufficiency, while the isolated steroidal sapogenins, ruscogenin and neoruscogenin, are applied against haemorrhoids. Increase of the venous tone and stimulation of the lymphatic transport are evident from pharmacological data. Several uncontrolled studies indicate efficacy of the isolated sapogenins in the treatment of haemorrhoids. A double-blind study on healthy volunteers showed a significant decrease in venous capacity and tissue volume. The efficacy of Ruscus aculeatus in the treatment of chronic venous insufficiency has not yet been proven in controlled clinical trials, as it has always been studied in combination with other active principles.
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