Quercetin and your skin

Lipolysis, blood circulation support, skin irritation, cellulite

Quercetin is a flavonoid found in many herbs, vegetables and fruits and is well researched for its antioxidant action and circulation supporting benefits. It has also been found to be a PDE4 inhibitor and therefore acts as a lipolytic. Finally, quercetin is well-known for its anti-irritation / anti-histamine action.


Quercetin cream

Quercetin is of great importance as an active ingredient in anti-cellulite, leg wellness, contouring and under-eye creams [the Celluence® creams are the only leg wellness / cellulite creams in the world with high concentrations of 95%+ pure quercetin, encased in liposomes, plus 39x other natural anti-cellulite actives].





2+ ways Quercetin

helps fight skin irritation, inflammation, oxidative damage, water retention and cellulite



2/ Quercetin, alone or with green tea extract EGCG, fights fat tissue inflammation...

...caused by high fat diet, by reducing proinflammatory gene expression.

[Source: Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice]



1/ Quercetin PREVENTS mitochondria-related health dysfunction...

...by protecting mitochondria from oxidative stress, by helping regulate mitochondrial metabolism and biogenesis, and by modulating cell apoptosis due to mitochondrial dysfunction [Source: Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease]


Screening of potential anti-adipogenic effects of phenolic compounds showing different chemical structure in 3T3-L1 preadipocytes

This study was designed to analyze the anti-adipogenic effect of fifteen phenolic compounds from various chemical groups in 3T3-L1 pre-adipocytes. Cells were treated with 25 μM, 10 μM or 1 μM of apigenin, luteolin, catechin, epicatechin, epigallocatechin, genistein, daizein, naringenin, hesperidin, quercetin, kaempferol, resveratrol, vanillic acid, piceatannol and pterostilbene for 8 days. At 25 μM lipid accumulation was reduced by all the compounds, with the exception of catechin, epicatechin and epigallocatechin. At a dose of 10 μM apigenin, luteolin, naringenin, hesperidin, quercetin and kaempferol induced significant reductions, and at 1 μM only naringenin, hesperidin and quercetin were effective. The expression of c/ebpα was not. C/ebpβ was significantly reduced by genistein and kaempferol, pparγ by genistein and pterostilbene, srebp1c by luteolin, genistein, hesperidin, kaempferol, pterostilbene and vanillic acid, and lpl by kaempferol. In conclusion, the most effective phenolic compounds are naringenin, hesperidin and quercetin. Differences were found in terms of effects on the expression of genes involved in adipogenesis among the analyzed compounds.